Microbial inorganic pyrophosphatases.

INTRODUCTION........................................... 169 INTRACELLULAR LOCALIZATION........................................... 169 REGULATION OF PPase SYNTHESIS........................................... 170 Effects of Culture Conditions ........................................... 170 PPase Mutants........................................... 170 Inhibition of Cell Division and Macromolecular Synthesis .......... ................. 171 POLYMORPHIC FORMS OF PPase ........................................... 171 REGULATION AT THE ACTIVITY LEVEL ....................................... 171 Problems Encountered in Kinetic Studies.......................................... 171 Kinetic Survey........................................... 172 Allosteric PPases................................................ 173 Regulation of PPase Activity by Adenylate Nucleotides .............................. 174 Regulation of PPase Activity by Glutathione ....................................... 175 SUMMARY........................................... 175 ACKNOWLEDGMENTS : ........................................... 176 LITERATURE CITED ........... ................................ 176